个人简介
李文山，中共党员，博士，太阳成集团tyc7111cc讲师，硕士生导师。
在SCI收录杂志ACS applied materials & interfaces、Chemistry Communications上发表论文多篇，申请国家发明专利1项。
主讲课程
现代仪器分析 免疫学
研究方向
1、功能性纳米材料在食品领域的分析检测应用
2、食品污染物的快速检测
主要代表性论文
(1) Wenshan Li ; Lei Luo; Jin Huang; Qing Wang; Jianbo Liu; Xiao Xiao; Hongmei Fang; Xiaohai Yang ; Kemin Wang , Self-assembled DNA nanocentipede as multivalent vehicle for enhanced delivery of CpG oligonucleotides, Chemical Communications, 2017, 53(40): 5565–5568
(2) Wenshan Li ; Xiaohai Yang ; Leiliang He; Kemin Wang ; Qing Wang; Jin Huang; Jianbo Liu; Bin Wu; Congcong Xu, Self-assembled DNA nanocentipede as multivalent drug carrier for targeted delivery, ACS Applied Materials & Interfaces, 2016, 8(39): 25733–25740
(3) Min Lin ; Wenshan Li ; Yaning Wang; Xiaohai Yang ; Kemin Wang ; Qing Wang; Pei Wang; Yujie Chang; Yuyu Tan, Discrimination of Hemoglobins with Subtle Differences Using an Aptamer Based Sensing Array, Chemical Communications, 2015, 51(39): 8304–8306
(4) Hongmei Fang ; Nuli Xie ; Min Ou; Jin Huang; Qing Wang; Wenshan Li； Jianbo Liu; Xiaohai Yang ; Kemin Wang, Detection of Nucleic Acids in Complex Samples via Magnetic Microbead-assisted Catalyzed Hairpin Assembly and “DD-A”FRET, Analytical Chemistry, 2018.5.21, 13(19): 2037–2044
(5) Li Bingjie ; Feng Zhenzhen; He Leiliang; Li Wenshan; Wang Qing; Liu Jianbo; Huang Jin; Zheng Yan; Ma Yanyun; Yang Xiaohai ; Wang Kemin , Self-Assembled Supramolecular Nanoparticles for Targeted Delivery and Combination Chemotherapy, ChemMedChem, 2018.7.19, 13(19): 2037–2044
(6) Bin Wu, Rui Jiang, Qing Wang, Jin Huang, Xiaohai Yang, Kemin Wang, Wenshan Li, Nandi Chen and Qing Li. Detection of C-Reactive Protein Using Nanoparticle-Enhanced Surface Plasmon Resonance Using an Aptamer-Antibody Sandwich Assay. Chemical Communications, 2016, 52, 3568−3571.
(7) Leiliang He, Xiaohai Yang, Fang Zhao, Kemin Wang, Qing Wang, Jianbo Liu, Jin Huang, Wenshan Li, and Meng Yang. Self-Assembled Supramolecular Nanoprobes for Ratiometric Fluorescence Measurement of Intracellular pH Values. Analytical Chemistry, 2015, 87, 2459−2465.
(8) Xiaochen Guo, Xiaohai Yang, Pei Liu, Kemin Wang, Qing Wang, Qiuping Guo, Jin Huang, Wenshan Li, Fengzhou Xu and Chunxia Song. Multiple Amplification Detection of MicroRNA Based on the Host–Guest Interaction Between β-Cyclodextrin Polymer and Pyrene. Analyst, 2015, 140, 4291–4297.
(9) Bin Wu, Nandi Chen, Qing Wang, Xiaohai Yang,Kemin Wang, Wenshan Li, Qing Li, Wenjing Liu and Hongmei Fang. A Simple Label-Free Aptamer-Based Method for Creactive Protein Detection. Analytical Methods, 2016, 8, 4177–4180.
(10) Haihua Huang, Xiaohai Yang, Kemin Wang, Qing Wang, Qiuping Guo, Jin Huang, Jianbo Liu, Xiaochen Guo, Wenshan Li, Leiliang He. Amplified Fluorescence Detection of DNA Based on Catalyzed Dynamic Assembly and Host–Guest Interaction Between β-Cyclodextrin Polymer and Pyrene. Talanta, 2015, 144, 529–534.
(11) Xiaochen Guo, Pei Liu, Xiaohai Yang, Kemin Wang, Qing Wang, Qiuping Guo, Jin Huang, Jianbo Liu, Chunxia Song and Wenshan Li. A Multiple Amplification Strategy for Nucleic Acid Detection Based on Host–Guest Interaction Between the β-Cyclodextrin Polymer and Pyrene, Analyst, 2015, 140, 2016–2022.
发明专利
(1) 羊小海; 李文山; 何磊良; 王青; 王柯敏; 黄晋; 刘剑波; 吴斌; 徐聪聪, 靶向载体、靶向药物及靶向药物的应用、靶向探针及靶向探针的应用, 2016.8.8, 中国, CN201610643160.7
学术交流
(1) Wenshan Li, Self-Assembled “DNA Nanocentipede” as Multivalent Drug Carrier for Targeted Delivery. 2016 7rd International Symposium on Bioanalysis, Biomedical Engineering and Nanotechnolog (ISBBN 2016), Oral Report.
